Nuclear receptor
From Proteopedia
(Difference between revisions)
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The structure of the LBD is strongly conserved throughout the familly of nuclear receptors. | The structure of the LBD is strongly conserved throughout the familly of nuclear receptors. | ||
| - | It is a globular domain | + | It is a globular domain, mainly alpha |
<scene name='Nuclear_receptor/Nr-lbd-/1'>well folded</scene> | <scene name='Nuclear_receptor/Nr-lbd-/1'>well folded</scene> | ||
| - | + | composed of | |
| + | <scene name='Nuclear_receptor/Nr-lbd-alpha/1'>12 alpha-helices</scene> | ||
| + | arranged in a three layered sandwich, and a <scene name='Nuclear_receptor/Nr-lbd-beta/1'>beta-sheet</scene>. | ||
</StructureSection> | </StructureSection> | ||
<references/> | <references/> | ||
Revision as of 10:41, 6 September 2012
the nuclear receptors facts book [1]
Structure
DBD (DNA Binding Domain)
LBD (Ligand Binding Domain)
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- ↑ Vincent Laudet, Hinrich Gronemeyer, "The nuclear receptor factsbook", Publisher Academic Press, 2002
