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== The Eukaryotic Chaperonin TRiC/CCT == | == The Eukaryotic Chaperonin TRiC/CCT == | ||
<StructureSection load='3iyg' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[3iyg]])' scene='Sandbox_Naama/Colored_tric/1'> | <StructureSection load='3iyg' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[3iyg]])' scene='Sandbox_Naama/Colored_tric/1'> | ||
| - | The TRiC/CCT [http://proteopedia/wiki/index.php/Chaperonin chaperonin] aids relatively 10% of the cellular proteome folding to their correct structure. | + | The TRiC/CCT [http://proteopedia/wiki/index.php/Chaperonin chaperonin] aids to relatively 10% of the cellular proteome folding to their correct structure. |
The uniqe structure of the mamalian chaperonine TRic/CCT was first published in 2010 by Cong Y et al<ref>pmid:020194787</ref>. it was determined in a low resolution of 4.7 A by cryo-EM. It is composed of <scene name='Sandbox_Naama/Tric_dimer/1'> two identical heterooligomer </scene> ring shaped subunits consisting of eight different paralogous subunits <scene name='Sandbox_Naama/One_subunit/2'>view one subunit</scene> /<scene name='Sandbox_Naama/Colored_tric/1'>view full protein</scene> | The uniqe structure of the mamalian chaperonine TRic/CCT was first published in 2010 by Cong Y et al<ref>pmid:020194787</ref>. it was determined in a low resolution of 4.7 A by cryo-EM. It is composed of <scene name='Sandbox_Naama/Tric_dimer/1'> two identical heterooligomer </scene> ring shaped subunits consisting of eight different paralogous subunits <scene name='Sandbox_Naama/One_subunit/2'>view one subunit</scene> /<scene name='Sandbox_Naama/Colored_tric/1'>view full protein</scene> | ||
Current revision
The Eukaryotic Chaperonin TRiC/CCT
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- ↑ Cong Y, Baker ML, Jakana J, Woolford D, Miller EJ, Reissmann S, Kumar RN, Redding-Johanson AM, Batth TS, Mukhopadhyay A, Ludtke SJ, Frydman J, Chiu W. 4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement. Proc Natl Acad Sci U S A. 2010 Mar 1. PMID:20194787
