3vjr
From Proteopedia
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| - | [[Image:3vjr.jpg|left|200px]] | ||
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{{STRUCTURE_3vjr| PDB=3vjr | SCENE= }} | {{STRUCTURE_3vjr| PDB=3vjr | SCENE= }} | ||
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===Crystal structure of Peptidyl-tRNA hydrolase from Escherichia coli in complex with the CCA-acceptor-T[PSI]C domain of tRNA=== | ===Crystal structure of Peptidyl-tRNA hydrolase from Escherichia coli in complex with the CCA-acceptor-T[PSI]C domain of tRNA=== | ||
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{{ABSTRACT_PUBMED_22923517}} | {{ABSTRACT_PUBMED_22923517}} | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/PTH_ECOLI PTH_ECOLI]] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death. | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3vjr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3vjr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VJR OCA]. |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022923517</ref><references group="xtra"/><references/> | ||
[[Category: Aminoacyl-tRNA hydrolase]] | [[Category: Aminoacyl-tRNA hydrolase]] | ||
| - | [[Category: Escherichia coli]] | + | [[Category: Escherichia coli k-12]] |
[[Category: Ito, K.]] | [[Category: Ito, K.]] | ||
[[Category: Miura, K I.]] | [[Category: Miura, K I.]] | ||
[[Category: Mochizuki, M.]] | [[Category: Mochizuki, M.]] | ||
[[Category: Murakami, R.]] | [[Category: Murakami, R.]] | ||
| - | [[Category: Qi, H]] | + | [[Category: Qi, H.]] |
[[Category: Shimizu, Y.]] | [[Category: Shimizu, Y.]] | ||
[[Category: Uchiumi, T.]] | [[Category: Uchiumi, T.]] | ||
Revision as of 07:32, 30 June 2013
Contents |
Crystal structure of Peptidyl-tRNA hydrolase from Escherichia coli in complex with the CCA-acceptor-T[PSI]C domain of tRNA
Template:ABSTRACT PUBMED 22923517
Function
[PTH_ECOLI] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death.
About this Structure
3vjr is a 4 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Ito K, Murakami R, Mochizuki M, Qi H, Shimizu Y, Miura KI, Ueda T, Uchiumi T. Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase. Nucleic Acids Res. 2012 Aug 25. PMID:22923517 doi:10.1093/nar/gks790
