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== '''LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF ''P. CARINII'' DHFR COMPLEXES WITH FOLATE AND NADP+''' ==
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=== '''Human topoisomerase IIbeta in complex with DNA and etoposide''' ===
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<Structure load='1cd2' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /><!-- PLEASE DO NOT DELETE THIS TEMPLATE -->
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<Structure load='3qx3' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /><!-- PLEASE DO NOT DELETE THIS TEMPLATE -->
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<ref>PMID: 10194348</ref>
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<ref>PMID: 21778401</ref>
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==References==
==References==
<references />
<references />

Revision as of 18:43, 18 September 2012

Human topoisomerase IIbeta in complex with DNA and etoposide

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Drag the structure with the mouse to rotate

[1]

References

  1. ↑ Wu CC, Li TK, Farh L, Lin LY, Lin TS, Yu YJ, Yen TJ, Chiang CW, Chan NL. Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide. Science. 2011 Jul 22;333(6041):459-62. PMID:21778401 doi:10.1126/science.1204117
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