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== '''LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF ''P. CARINII'' DHFR COMPLEXES WITH FOLATE AND NADP+''' ==
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=== '''Human topoisomerase IIbeta in complex with DNA and etoposide''' ===
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<Structure load='1cd2' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /><!-- PLEASE DO NOT DELETE THIS TEMPLATE -->
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<Structure load='3qx3' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /><!-- PLEASE DO NOT DELETE THIS TEMPLATE -->
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<ref>PMID: 10194348</ref>
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<ref>PMID: 21778401</ref>
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==References==
==References==
<references />
<references />

Revision as of 18:43, 18 September 2012

Human topoisomerase IIbeta in complex with DNA and etoposide

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Drag the structure with the mouse to rotate

[1]

References

  1. Wu CC, Li TK, Farh L, Lin LY, Lin TS, Yu YJ, Yen TJ, Chiang CW, Chan NL. Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide. Science. 2011 Jul 22;333(6041):459-62. PMID:21778401 doi:10.1126/science.1204117
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