Fragment-Based Drug Discovery

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Click on each amino acid to view the hydrophobic interactions with the ligand:
Click on each amino acid to view the hydrophobic interactions with the ligand:
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•<scene name='Sandbox_reserved_394/Tyrosine_199/3'>Tyr199</scene>
+
{{multiCol}}•<scene name='Sandbox_reserved_394/Tyrosine_199/3'>Tyr199</scene>{{colBreak}}
 +
•<scene name='Sandbox_reserved_394/Valine_145/1'>Val145</scene>{{endMultiCol}}
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•<scene name='Sandbox_reserved_394/Valine_145/1'>Val145</scene>
+
{{multiCol}}•<scene name='Sandbox_reserved_394/Leucine_134/1'>Leu134</scene>{{colBreak}}
 +
•<scene name='Sandbox_reserved_394/Phe109_and_ala108/1'>Phe109</scene>{{endMultiCol}}
-
•<scene name='Sandbox_reserved_394/Leucine_134/1'>Leu134</scene>
+
{{multiCol}}•<scene name='Sandbox_reserved_394/Phe109_and_ala108/1'>Ala108</scene>{{colBreak}}
 +
•<scene name='Sandbox_reserved_394/Tyrosine_105/1'>Tyr105</scene>{{endMultiCol}}
-
•<scene name='Sandbox_reserved_394/Phe109_and_ala108/1'>Phe109</scene>
+
{{multiCol}}•<scene name='Sandbox_reserved_394/Phe_101/1'>Phe101</scene>{{colBreak}}
-
 
+
•<scene name='Sandbox_reserved_394/Glycine_142/1'>Gly142</scene>{{endMultiCol}}
-
•<scene name='Sandbox_reserved_394/Phe109_and_ala108/1'>Ala108</scene>
+
-
 
+
-
•<scene name='Sandbox_reserved_394/Tyrosine_105/1'>Tyr105</scene>
+
-
 
+
-
•<scene name='Sandbox_reserved_394/Phe_101/1'>Phe101</scene>
+
</StructureSection>
</StructureSection>

Revision as of 23:07, 25 September 2012

Paclitaxel in Apoptosis

Structure of HMG-CoA reductase (PDB entry 1ysi)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Justin Weekley, Arthur Cox, Jaime Prilusky

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