4feu
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:4feu.png|left|200px]] | ||
| - | |||
{{STRUCTURE_4feu| PDB=4feu | SCENE= }} | {{STRUCTURE_4feu| PDB=4feu | SCENE= }} | ||
| - | |||
===Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor anthrapyrazolone SP600125=== | ===Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor anthrapyrazolone SP600125=== | ||
| + | {{ABSTRACT_PUBMED_23758273}} | ||
| + | ==About this Structure== | ||
| + | [[4feu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Acinetobacter_baumannii_aye Acinetobacter baumannii aye]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEU OCA]. | ||
| - | == | + | ==Reference== |
| - | + | <ref group="xtra">PMID:023758273</ref><references group="xtra"/><references/> | |
| - | [[Category: Acinetobacter baumannii]] | + | [[Category: Acinetobacter baumannii aye]] |
[[Category: Kanamycin kinase]] | [[Category: Kanamycin kinase]] | ||
[[Category: Anderson, W F.]] | [[Category: Anderson, W F.]] | ||
Revision as of 07:28, 30 June 2013
Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor anthrapyrazolone SP600125
Template:ABSTRACT PUBMED 23758273
About this Structure
4feu is a 6 chain structure with sequence from Acinetobacter baumannii aye. Full crystallographic information is available from OCA.
Reference
- Stogios PJ, Spanogiannopoulos P, Evdokimova E, Egorova O, Shakya T, Todorovic N, Capretta A, Wright GD, Savchenko A. Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem J. 2013 Jun 12. PMID:23758273 doi:10.1042/BJ20130317
Categories: Acinetobacter baumannii aye | Kanamycin kinase | Anderson, W F. | CSGID, Center for Structural Genomics of Infectious Diseases. | Egorova, O. | Evdokimova, E. | Leo, R Di. | Minasov, G. | Savchenko, A. | Shakya, T. | Spanogiannopoulos, P. | Stogios, P J. | Wawrzak, Z. | Wright, G D. | Alpha/beta protein | Aminoglycoside phosphotransferase | Aminoglycoside | Anthrapyrazolone | Antibiotic resistance | Center for structural genomics of infectious disease | Csgid | Eukaryotic protein kinase-like fold | Gtp | Intracellular | Kanamycin | National institute of allergy and infectious disease | Niaid | Phosphotransferase | Protein kinase inhibitor | Sp600125 | Transferase | Transferase-transferase inhibitor complex
