3u4h

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3u4h.jpg|left|200px]]
 
- 
{{STRUCTURE_3u4h| PDB=3u4h | SCENE= }}
{{STRUCTURE_3u4h| PDB=3u4h | SCENE= }}
- 
===CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template===
===CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template===
 +
{{ABSTRACT_PUBMED_23840430}}
 +
==Function==
 +
[[http://www.uniprot.org/uniprot/CD38_HUMAN CD38_HUMAN]] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
==About this Structure==
==About this Structure==
-
[[3u4h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U4H OCA].
+
[[3u4h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U4H OCA].
 +
 
 +
==See Also==
 +
*[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]]
 +
 
 +
==Reference==
 +
<ref group="xtra">PMID:023840430</ref><references group="xtra"/><references/>
 +
[[Category: Homo sapiens]]
[[Category: Graeff, R.]]
[[Category: Graeff, R.]]
[[Category: Hao, Q.]]
[[Category: Hao, Q.]]

Revision as of 11:04, 24 July 2013

Template:STRUCTURE 3u4h

Contents

CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template

Template:ABSTRACT PUBMED 23840430

Function

[CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

About this Structure

3u4h is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Moreau C, Liu Q, Graeff R, Wagner GK, Thomas MP, Swarbrick JM, Shuto S, Lee HC, Hao Q, Potter BV. CD38 Structure-Based Inhibitor Design Using the 1-Cyclic Inosine 5'-Diphosphate Ribose Template. PLoS One. 2013 Jun 19;8(6):e66247. Print 2013. PMID:23840430 doi:10.1371/journal.pone.0066247

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3u4h"
Personal tools