Insulin receptor
From Proteopedia
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'''Insulin receptor''' (IR) is a transmembrane receptor activated by insulin, IGF-I and IGF-II. IR is important for the regulation of glucose homeostasis and its malfunction can cause diabetics and cancer. The IR is a dimer where each monomer contains 8 distinct domains. The beta-chain contains a tyrosine kinase catalytic domain (TK). | '''Insulin receptor''' (IR) is a transmembrane receptor activated by insulin, IGF-I and IGF-II. IR is important for the regulation of glucose homeostasis and its malfunction can cause diabetics and cancer. The IR is a dimer where each monomer contains 8 distinct domains. The beta-chain contains a tyrosine kinase catalytic domain (TK). | ||
Revision as of 09:48, 5 November 2012
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