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3vwd

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'''Unreleased structure'''
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{{STRUCTURE_3vwd| PDB=3vwd | SCENE= }}
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===Crystal structure of alpha-tubulin acetyltransferase domain of human Mec-17 in complex with acetoacetyl-CoA (P21212 form)===
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The entry 3vwd is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/ATAT_HUMAN ATAT_HUMAN]] Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development.<ref>PMID:20829795</ref>
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Authors: Yuzawa, S., Sumimoto, H.
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==About this Structure==
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[[3vwd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VWD OCA].
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Description: Crystal structure of alpha-tubulin acetyltransferase domain of human Mec-17 in complex with acetoacetyl-CoA (P21212 form)
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Alpha-tubulin N-acetyltransferase]]
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[[Category: Homo sapiens]]
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[[Category: Sumimoto, H.]]
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[[Category: Yuzawa, S.]]
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[[Category: Acetyltransferase]]
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[[Category: Gnat fold]]
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[[Category: Transferase]]

Revision as of 07:34, 28 August 2013

Template:STRUCTURE 3vwd

Contents

Crystal structure of alpha-tubulin acetyltransferase domain of human Mec-17 in complex with acetoacetyl-CoA (P21212 form)

Function

[ATAT_HUMAN] Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development.[1]

About this Structure

3vwd is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Akella JS, Wloga D, Kim J, Starostina NG, Lyons-Abbott S, Morrissette NS, Dougan ST, Kipreos ET, Gaertig J. MEC-17 is an alpha-tubulin acetyltransferase. Nature. 2010 Sep 9;467(7312):218-22. doi: 10.1038/nature09324. PMID:20829795 doi:10.1038/nature09324

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OCA

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