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4g5f

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'''Unreleased structure'''
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{{STRUCTURE_4g5f| PDB=4g5f | SCENE= }}
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===Pantothenate synthetase in complex with racemate (2S)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID and (2R)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID===
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The entry 4g5f is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref>
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Authors: Silvestre, H.L., Blundell, T.L., Abell, C., Ciulli, A.
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==About this Structure==
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[[4g5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G5F OCA].
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Description: Pantothenate synthetase in complex with racemate fragment 6
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Abell, C.]]
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[[Category: Blundell, T L.]]
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[[Category: Ciulli, A.]]
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[[Category: Silvestre, H L.]]
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[[Category: Atp binding pantoate binding beta-alanine binding]]
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[[Category: Ligase]]
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[[Category: Ligase-ligase inhibitor complex]]

Revision as of 05:03, 18 July 2013

Template:STRUCTURE 4g5f

Contents

Pantothenate synthetase in complex with racemate (2S)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID and (2R)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID

Function

[PANC_MYCTU] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.[1]

About this Structure

4g5f is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. ↑ Zheng R, Blanchard JS. Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase. Biochemistry. 2001 Oct 30;40(43):12904-12. PMID:11669627

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