Sandbox 39
From Proteopedia
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<Structure load='1AKE' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='1AKE' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
| - | Adenylate kinase plays an important role in nucleotide metabolism in many organisms. It also has a role in cellular energetics by phosphotransfer networks. | + | =Description= |
| + | Adenylate kinase, commonly known as ADK, is a phosphotransferase enzyme. It has two important roles in the body. First, ADK plays an important role in nucleotide metabolism in many organisms. It also has a role in cellular energetics and homeostasis by phosphotransfer networks. Adenylate kinase catalyzes the reaction that forms ADP. The reaction is ATP + AMP = 2 ADP. In this catalyzed reaction, ADK molecules bind to AMP molecules and increase its binding affinity for ATP over other phosphate groups. However, adenylate kinase is also found in other molecules such as bacteria and yeast. ADK plays similar roles in bacteria and yeast, in that it involves cellular metabolism and energy. The following images highlight the structure of Adenylate kinase from ''Yersinia pestis''. | ||
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<scene name='Sandbox_39/Adenylate_kinase_beta_sheets2/1'>Secondary Structure</scene> | <scene name='Sandbox_39/Adenylate_kinase_beta_sheets2/1'>Secondary Structure</scene> | ||
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<scene name='Sandbox_39/Adenylate_kinase_ligand/1'>Ligand</scene> | <scene name='Sandbox_39/Adenylate_kinase_ligand/1'>Ligand</scene> | ||
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Revision as of 03:23, 18 October 2012
| Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013. |
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Description
Adenylate kinase, commonly known as ADK, is a phosphotransferase enzyme. It has two important roles in the body. First, ADK plays an important role in nucleotide metabolism in many organisms. It also has a role in cellular energetics and homeostasis by phosphotransfer networks. Adenylate kinase catalyzes the reaction that forms ADP. The reaction is ATP + AMP = 2 ADP. In this catalyzed reaction, ADK molecules bind to AMP molecules and increase its binding affinity for ATP over other phosphate groups. However, adenylate kinase is also found in other molecules such as bacteria and yeast. ADK plays similar roles in bacteria and yeast, in that it involves cellular metabolism and energy. The following images highlight the structure of Adenylate kinase from Yersinia pestis.
