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3ef1

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[[Image:3ef1.png|left|200px]]
 
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{{STRUCTURE_3ef1| PDB=3ef1 | SCENE= }}
{{STRUCTURE_3ef1| PDB=3ef1 | SCENE= }}
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===The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase===
===The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase===
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{{ABSTRACT_PUBMED_19026779}}
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{{ABSTRACT_PUBMED_019026779}}
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==Function==
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[[http://www.uniprot.org/uniprot/FCP1_SCHPO FCP1_SCHPO]] Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II.
==About this Structure==
==About this Structure==
[[3ef1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EF1 OCA].
[[3ef1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EF1 OCA].
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==See Also==
 
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*[[RNA polymerase|RNA polymerase]]
 
==Reference==
==Reference==
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<ref group="xtra">PMID:019026779</ref><references group="xtra"/>
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<ref group="xtra">PMID:019026779</ref><references group="xtra"/><references/>
[[Category: Phosphoprotein phosphatase]]
[[Category: Phosphoprotein phosphatase]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]

Revision as of 13:22, 19 June 2013

Template:STRUCTURE 3ef1

Contents

The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase

Template:ABSTRACT PUBMED 19026779

Function

[FCP1_SCHPO] Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II.

About this Structure

3ef1 is a 1 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.

Reference

  • Ghosh A, Shuman S, Lima CD. The structure of Fcp1, an essential RNA polymerase II CTD phosphatase. Mol Cell. 2008 Nov 21;32(4):478-90. PMID:19026779 doi:10.1016/j.molcel.2008.09.021

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