1l1s
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1l1s.gif|left|200px]] | + | [[Image:1l1s.gif|left|200px]] |
| - | + | ||
| - | '''Structure of Protein of Unknown Function MTH1491 from Methanobacterium thermoautotrophicum''' | + | {{Structure |
| + | |PDB= 1l1s |SIZE=350|CAPTION= <scene name='initialview01'>1l1s</scene>, resolution 2.30Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= ORF1491 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=145262 Methanothermobacter thermautotrophicus]) | ||
| + | }} | ||
| + | |||
| + | '''Structure of Protein of Unknown Function MTH1491 from Methanobacterium thermoautotrophicum''' | ||
| + | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1L1S is a [ | + | 1L1S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1S OCA]. |
==Reference== | ==Reference== | ||
| - | The crystal structure of hypothetical protein MTH1491 from Methanobacterium thermoautotrophicum., Christendat D, Saridakis V, Kim Y, Kumar PA, Xu X, Semesi A, Joachimiak A, Arrowsmith CH, Edwards AM, Protein Sci. 2002 Jun;11(6):1409-14. PMID:[http:// | + | The crystal structure of hypothetical protein MTH1491 from Methanobacterium thermoautotrophicum., Christendat D, Saridakis V, Kim Y, Kumar PA, Xu X, Semesi A, Joachimiak A, Arrowsmith CH, Edwards AM, Protein Sci. 2002 Jun;11(6):1409-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12021439 12021439] |
[[Category: Methanothermobacter thermautotrophicus]] | [[Category: Methanothermobacter thermautotrophicus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 26: | Line 35: | ||
[[Category: hypothetical protein]] | [[Category: hypothetical protein]] | ||
[[Category: mcsg]] | [[Category: mcsg]] | ||
| - | [[Category: midwest center for structural | + | [[Category: midwest center for structural genomic]] |
[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
[[Category: psi]] | [[Category: psi]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:25:10 2008'' |
Revision as of 10:25, 20 March 2008
| |||||||
| , resolution 2.30Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | ORF1491 (Methanothermobacter thermautotrophicus) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of Protein of Unknown Function MTH1491 from Methanobacterium thermoautotrophicum
Overview
As part of our structural proteomics initiative, we have determined the crystal structure of MTH1491, a previously uncharacterized hypothetical protein from Methanobacterium thermoautotrophicum. MTH1491 is one of numerous structural genomics targets selected in a genome-wide survey of uncharacterized proteins. It belongs to a family of proteins whose biological function is not known. The crystal structure of MTH1491, the first structure for this family of proteins, consists of an overall five-stranded parallel beta-sheet with strand order 51234 and flanking helices. The oligomeric form of this molecule is a trimer as seen from both crystal contacts and gel filtration studies. Analysis revealed that the structure of MTH1491 is similar to that of dehydrogenases, amidohydrolases, and oxidoreductases. Using a combination of sequence and structural analyses, we showed that MTH1491 does not belong to either the dehydrogenase or the amidohydrolase superfamilies of proteins.
About this Structure
1L1S is a Single protein structure of sequence from Methanothermobacter thermautotrophicus. Full crystallographic information is available from OCA.
Reference
The crystal structure of hypothetical protein MTH1491 from Methanobacterium thermoautotrophicum., Christendat D, Saridakis V, Kim Y, Kumar PA, Xu X, Semesi A, Joachimiak A, Arrowsmith CH, Edwards AM, Protein Sci. 2002 Jun;11(6):1409-14. PMID:12021439
Page seeded by OCA on Thu Mar 20 12:25:10 2008
Categories: Methanothermobacter thermautotrophicus | Single protein | Arrowsmith, C H. | Christendat, D. | Edwards, A M. | Joachimiak, A. | Kim, Y. | Kumar, P A. | MCSG, Midwest Center for Structural Genomics. | Saridakis, V. | Semesi, A. | Xu, X. | Crystal structure | Hypothetical protein | Mcsg | Midwest center for structural genomic | Protein structure initiative | Psi | Structural genomic
