This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1l3a
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1l3a.jpg|left|200px]] | + | [[Image:1l3a.jpg|left|200px]] |
| - | + | ||
| - | '''Structure of the plant transcriptional regulator PBF-2''' | + | {{Structure |
| + | |PDB= 1l3a |SIZE=350|CAPTION= <scene name='initialview01'>1l3a</scene>, resolution 2.30Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Structure of the plant transcriptional regulator PBF-2''' | ||
| + | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1L3A is a [ | + | 1L3A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3A OCA]. |
==Reference== | ==Reference== | ||
| - | A new family of plant transcription factors displays a novel ssDNA-binding surface., Desveaux D, Allard J, Brisson N, Sygusch J, Nat Struct Biol. 2002 Jul;9(7):512-7. PMID:[http:// | + | A new family of plant transcription factors displays a novel ssDNA-binding surface., Desveaux D, Allard J, Brisson N, Sygusch J, Nat Struct Biol. 2002 Jul;9(7):512-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12080340 12080340] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Solanum tuberosum]] | [[Category: Solanum tuberosum]] | ||
| Line 24: | Line 33: | ||
[[Category: whirly]] | [[Category: whirly]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:25:45 2008'' |
Revision as of 10:25, 20 March 2008
| |||||||
| , resolution 2.30Å | |||||||
|---|---|---|---|---|---|---|---|
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of the plant transcriptional regulator PBF-2
Overview
The crystal structure of p24, the single-stranded DNA (ssDNA) binding subunit of the plant defense transcription factor PBF-2, has been determined to 2.3 A resolution. p24 is representative of a novel family of ubiquitous plant-specific proteins that we refer to as the Whirly family because of their quaternary structure. PBF-2 is composed of four p24 molecules that interact through a helix-loop-helix motif. This interaction produces a central pore, with beta-strands radiating outwards, resulting in a whirligig appearance to the quaternary structure. The noncrystallographic C(4) symmetry arrangement of p24 subunits is novel for ssDNA binding proteins and may explain the binding specificity of PBF-2. This structural arrangement also supports the role of PBF-2 in binding melted promoter regions to modulate gene expression.
About this Structure
1L3A is a Single protein structure of sequence from Solanum tuberosum. Full crystallographic information is available from OCA.
Reference
A new family of plant transcription factors displays a novel ssDNA-binding surface., Desveaux D, Allard J, Brisson N, Sygusch J, Nat Struct Biol. 2002 Jul;9(7):512-7. PMID:12080340
Page seeded by OCA on Thu Mar 20 12:25:45 2008
