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1apu
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystallographic analysis of a pepstatin analogue binding to the aspartyl proteinase penicillopepsin at 1.8 angstroms resolution== | |
| - | + | <StructureSection load='1apu' size='340' side='right' caption='[[1apu]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1apu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Penja Penja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1APU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1APU FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=32L:ETHYL+(3S,4S)-4-AMINO-3-HYDROXY-6-METHYLHEPTANOATE'>32L</scene>, <scene name='pdbligand=IVA:ISOVALERIC+ACID'>IVA</scene></td></tr> | |
| - | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1apt|1apt]], [[1apv|1apv]], [[1apw|1apw]]</td></tr> | |
| - | == | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillopepsin Penicillopepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.20 3.4.23.20] </span></td></tr> |
| - | [[1apu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1apu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1apu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1apu RCSB], [http://www.ebi.ac.uk/pdbsum/1apu PDBsum]</span></td></tr> |
| + | <table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ap/1apu_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Penicillopepsin|Penicillopepsin]] | *[[Penicillopepsin|Penicillopepsin]] | ||
*[[Pepsin|Pepsin]] | *[[Pepsin|Pepsin]] | ||
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Penicillopepsin]] | [[Category: Penicillopepsin]] | ||
| + | [[Category: Penja]] | ||
[[Category: James, M N.G.]] | [[Category: James, M N.G.]] | ||
[[Category: Sielecki, A R.]] | [[Category: Sielecki, A R.]] | ||
[[Category: Acid proteinase]] | [[Category: Acid proteinase]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 04:30, 4 June 2014
Crystallographic analysis of a pepstatin analogue binding to the aspartyl proteinase penicillopepsin at 1.8 angstroms resolution
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