3kle
From Proteopedia
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{{STRUCTURE_3kle| PDB=3kle | SCENE= }} | {{STRUCTURE_3kle| PDB=3kle | SCENE= }} | ||
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===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA=== | ===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA=== | ||
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{{ABSTRACT_PUBMED_20852643}} | {{ABSTRACT_PUBMED_20852643}} | ||
Revision as of 09:07, 11 March 2013
Contents |
Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA
Template:ABSTRACT PUBMED 20852643
About this Structure
3kle is a 16 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908
Categories: Human immunodeficiency virus 1 | Arnold, E. | Das, K. | Sarafianos, S G. | Tu, X. | Aid | Azt | Azt adenosine dinucleoside tetraphosphate | Azt resistance mechanism | Aztp4a | Aztppppa | Dna polymerase | Dna-directed dna polymerase | Endonuclease | Hiv | Hiv-1 | Hydrolase | Magnesium | Metal-binding | Multifunctional enzyme | Myristate | Nrti | Nrti resistance | Nuclease | Nucleoside inhibitor | Nucleotide excision | P51/p66 | Resistance mutation | Reverse transcriptase | Rna-directed dna polymerase | Rt | Thymidine analog mutation | Transferase | Transferase-dna complex
