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2xzm

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[[Image:2xzm.png|left|200px]]
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==CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH INITIATION FACTOR 1. THIS FILE CONTAINS THE 40S SUBUNIT AND INITIATION FACTOR FOR MOLECULE 1==
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<StructureSection load='2xzm' size='340' side='right' caption='[[2xzm]], [[Resolution|resolution]] 3.93&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2xzm]] is a 35 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XZM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xzn|2xzn]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xzm RCSB], [http://www.ebi.ac.uk/pdbsum/2xzm PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Eukaryotic ribosomes are substantially larger and more complex than their bacterial counterparts. Although their core function is conserved, bacterial and eukaryotic protein synthesis differ considerably at the level of initiation. The eukaryotic small ribosomal subunit (40S) plays a central role in this process; it binds initiation factors that facilitate scanning of messenger RNAs and initiation of protein synthesis. We have determined the crystal structure of the Tetrahymena thermophila 40S ribosomal subunit in complex with eukaryotic initiation factor 1 (eIF1) at 3.9 A resolution. The structure reveals the fold of the entire 18S rRNA and of all ribosomal proteins of the 40S subunit and defines the interactions with the eIF1. It provides insights into the eukaryotic-specific aspects of protein synthesis including the function of eIF1, and signaling and regulation mediated by ribosomal proteins RACK1 and rpS6e.
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{{STRUCTURE_2xzm| PDB=2xzm | SCENE= }}
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Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1.,Rabl J, Leibundgut M, Ataide SF, Haag A, Ban N Science. 2010 Dec 23. PMID:21205638<ref>PMID:21205638</ref>
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===CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH INITIATION FACTOR 1. THIS FILE CONTAINS THE 40S SUBUNIT AND INITIATION FACTOR FOR MOLECULE 1===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_21205638}}
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==About this Structure==
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[[2xzm]] is a 35 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZM OCA].
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==See Also==
==See Also==
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*[[Ribosomal protein S10|Ribosomal protein S10]]
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*[[Ribosome 3D structures|Ribosome 3D structures]]
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*[[Ribosomal protein S11|Ribosomal protein S11]]
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== References ==
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*[[Ribosomal protein S12|Ribosomal protein S12]]
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<references/>
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*[[Ribosomal protein S17|Ribosomal protein S17]]
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__TOC__
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*[[Ribosomal protein S2|Ribosomal protein S2]]
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</StructureSection>
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*[[Ribosomal protein S24|Ribosomal protein S24]]
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*[[Ribosomal protein S28|Ribosomal protein S28]]
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*[[Ribosomal protein S3|Ribosomal protein S3]]
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*[[Ribosomal protein S4|Ribosomal protein S4]]
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*[[Ribosomal protein S5|Ribosomal protein S5]]
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*[[Ribosomal protein S7|Ribosomal protein S7]]
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*[[Ribosomal protein S8|Ribosomal protein S8]]
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==Reference==
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<ref group="xtra">PMID:021205638</ref><references group="xtra"/>
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[[Category: Tetrahymena thermophila]]
[[Category: Tetrahymena thermophila]]
[[Category: Ataide, S F.]]
[[Category: Ataide, S F.]]

Revision as of 13:21, 22 October 2014

CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH INITIATION FACTOR 1. THIS FILE CONTAINS THE 40S SUBUNIT AND INITIATION FACTOR FOR MOLECULE 1

2xzm, resolution 3.93Å

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