2w7x
From Proteopedia
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{{STRUCTURE_2w7x| PDB=2w7x | SCENE= }} | {{STRUCTURE_2w7x| PDB=2w7x | SCENE= }} | ||
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===CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019=== | ===CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019=== | ||
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{{ABSTRACT_PUBMED_19741151}} | {{ABSTRACT_PUBMED_19741151}} | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:019741151</ref><references group="xtra"/> | + | <ref group="xtra">PMID:019741151</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
Revision as of 00:55, 25 March 2013
Contents |
CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019
Template:ABSTRACT PUBMED 19741151
About this Structure
2w7x is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Jobson AG, Lountos GT, Lorenzi PL, Llamas J, Connelly J, Cerna D, Tropea JE, Onda A, Zoppoli G, Kondapaka S, Zhang G, Caplen NJ, Cardellina JH 2nd, Yoo SS, Monks A, Self C, Waugh DS, Shoemaker RH, Pommier Y. Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]. J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. Epub 2009 Sep 9. PMID:19741151 doi:10.1124/jpet.109.154997
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Caplen, N J. | Caredellina, J H. | Connelly, J. | Jobson, A G. | Kondapaka, S. | Llamas, J. | Lorenzi, P L. | Lountos, G T. | Monks, A. | Onda, A. | Pommier, Y. | Self, C. | Shoemaker, R H. | Tropea, J E. | Waugh, D S. | Zhang, G. | Atp-binding | Cell cycle | Chk2 inhibitor | Co-crystal structure | Disease mutation | Kinase | Li-fraumeni syndrome | Magnesium | Metal-binding | Nucleotide-binding | Nucleus | Phosphoprotein | Potentiation | Proto-oncogene | Serine/threonine-protein kinase | Transferase
