2vrm

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[[Image:2vrm.png|left|200px]]
 
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{{STRUCTURE_2vrm| PDB=2vrm | SCENE= }}
{{STRUCTURE_2vrm| PDB=2vrm | SCENE= }}
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===Structure of human MAO B in complex with phenyethylhydrazine===
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{{ABSTRACT_PUBMED_18426226}}
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===STRUCTURE OF HUMAN MAO B IN COMPLEX WITH PHENYETHYLHYDRAZINE===
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==Function==
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[[http://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN]] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
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{{ABSTRACT_PUBMED_18426226}}
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==About this Structure==
==About this Structure==
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[[2vrm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRM OCA].
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[[2vrm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRM OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:018426226</ref><references group="xtra"/>
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<ref group="xtra">PMID:018426226</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Monoamine oxidase]]
[[Category: Monoamine oxidase]]
[[Category: Binda, C.]]
[[Category: Binda, C.]]

Revision as of 08:15, 8 January 2014

Template:STRUCTURE 2vrm

Contents

Structure of human MAO B in complex with phenyethylhydrazine

Template:ABSTRACT PUBMED 18426226

Function

[AOFB_HUMAN] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.

About this Structure

2vrm is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See Also

Reference

  • Binda C, Wang J, Li M, Hubalek F, Mattevi A, Edmondson DE. Structural and Mechanistic Studies of Arylalkylhydrazine Inhibition of Human Monoamine Oxidases A and B. Biochemistry. 2008 Apr 22;. PMID:18426226 doi:http://dx.doi.org/10.1021/bi8002814

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