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1sp4
From Proteopedia
(Difference between revisions)
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| - | [[Image:1sp4.png|left|200px]] | ||
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{{STRUCTURE_1sp4| PDB=1sp4 | SCENE= }} | {{STRUCTURE_1sp4| PDB=1sp4 | SCENE= }} | ||
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===Crystal structure of NS-134 in complex with bovine cathepsin B: a two headed epoxysuccinyl inhibitor extends along the whole active site cleft=== | ===Crystal structure of NS-134 in complex with bovine cathepsin B: a two headed epoxysuccinyl inhibitor extends along the whole active site cleft=== | ||
| + | {{ABSTRACT_PUBMED_15084146}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/CATB_BOVIN CATB_BOVIN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:015084146</ref><references group="xtra"/> | + | <ref group="xtra">PMID:015084146</ref><references group="xtra"/><references/> |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Cathepsin B]] | [[Category: Cathepsin B]] | ||
Revision as of 03:33, 13 February 2014
Contents |
Crystal structure of NS-134 in complex with bovine cathepsin B: a two headed epoxysuccinyl inhibitor extends along the whole active site cleft
Template:ABSTRACT PUBMED 15084146
Function
[CATB_BOVIN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
About this Structure
1sp4 is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
See Also
Reference
- Stern I, Schaschke N, Moroder L, Turk D. Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. Biochem J. 2004 Jul 15;381(Pt 2):511-7. PMID:15084146 doi:10.1042/BJ20040237
