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3dtj

From Proteopedia

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[[Image:3dtj.png|left|200px]]
 
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{{STRUCTURE_3dtj| PDB=3dtj | SCENE= }}
{{STRUCTURE_3dtj| PDB=3dtj | SCENE= }}
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===HIV-1 capsid C-terminal domain mutant (E187A)===
===HIV-1 capsid C-terminal domain mutant (E187A)===
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{{ABSTRACT_PUBMED_18772135}}
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{{ABSTRACT_PUBMED_18772135}}
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==Function==
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[[http://www.uniprot.org/uniprot/Q72497_9HIV1 Q72497_9HIV1]] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).[SAAS:SAAS012344_004_011858]
==About this Structure==
==About this Structure==
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[[3dtj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DTJ OCA].
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[[3dtj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DTJ OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:018772135</ref><ref group="xtra">PMID:016041386</ref><references group="xtra"/>
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<ref group="xtra">PMID:018772135</ref><references group="xtra"/><references/>
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Hiv-1]]
[[Category: Igonet, S.]]
[[Category: Igonet, S.]]
[[Category: Rey, F A.]]
[[Category: Rey, F A.]]

Revision as of 04:17, 13 February 2014

Template:STRUCTURE 3dtj

Contents

HIV-1 capsid C-terminal domain mutant (E187A)

Template:ABSTRACT PUBMED 18772135

Function

[Q72497_9HIV1] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).[SAAS:SAAS012344_004_011858]

About this Structure

3dtj is a 4 chain structure with sequence from Hiv-1. Full crystallographic information is available from OCA.

See Also

Reference

  • Bartonova V, Igonet S, Sticht J, Glass B, Habermann A, Vaney MC, Sehr P, Lewis J, Rey FA, Krausslich HG. Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein. J Biol Chem. 2008 Nov 14;283(46):32024-33. Epub 2008 Sep 4. PMID:18772135 doi:10.1074/jbc.M804230200

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