1xrm
From Proteopedia
(Difference between revisions)
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| - | [[Image:1xrm.png|left|200px]] | ||
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{{STRUCTURE_1xrm| PDB=1xrm | SCENE= }} | {{STRUCTURE_1xrm| PDB=1xrm | SCENE= }} | ||
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===Crystal structure of active site F1-mutant E213Q soaked with peptide Ala-Phe=== | ===Crystal structure of active site F1-mutant E213Q soaked with peptide Ala-Phe=== | ||
| + | {{ABSTRACT_PUBMED_15994304}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/PIP_THEAC PIP_THEAC]] Cleaves H-Pro-AMC as well as a wide spectrum of amino acid substrates and several peptide substrates without a proline at the N-terminus. Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome) yielding free amino acids. | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1xrm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[1xrm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRM OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:015994304</ref><references group="xtra"/> | + | <ref group="xtra">PMID:015994304</ref><references group="xtra"/><references/> |
[[Category: Prolyl aminopeptidase]] | [[Category: Prolyl aminopeptidase]] | ||
| - | [[Category: Thermoplasma acidophilum]] | ||
[[Category: Brandstetter, H.]] | [[Category: Brandstetter, H.]] | ||
[[Category: Goehring, W.]] | [[Category: Goehring, W.]] | ||
Revision as of 07:29, 16 April 2014
Contents |
Crystal structure of active site F1-mutant E213Q soaked with peptide Ala-Phe
Template:ABSTRACT PUBMED 15994304
Function
[PIP_THEAC] Cleaves H-Pro-AMC as well as a wide spectrum of amino acid substrates and several peptide substrates without a proline at the N-terminus. Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome) yielding free amino acids.
About this Structure
1xrm is a 1 chain structure with sequence from "thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970. Full crystallographic information is available from OCA.
See Also
Reference
- Goettig P, Brandstetter H, Groll M, Gohring W, Konarev PV, Svergun DI, Huber R, Kim JS. X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum. J Biol Chem. 2005 Sep 30;280(39):33387-96. Epub 2005 Jul 1. PMID:15994304 doi:http://dx.doi.org/10.1074/jbc.M505030200
