This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1lud
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1lud.gif|left|200px]]< | + | [[Image:1lud.gif|left|200px]] |
| - | + | ||
| - | '''SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES''' | + | {{Structure |
| + | |PDB= 1lud |SIZE=350|CAPTION= <scene name='initialview01'>1lud</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene> and <scene name='pdbligand=TRR:2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM'>TRR</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES''' | ||
| + | |||
==About this Structure== | ==About this Structure== | ||
| - | 1LUD is a [ | + | 1LUD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LUD OCA]. |
==Reference== | ==Reference== | ||
| - | NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH., Polshakov VI, Smirnov EG, Birdsall B, Kelly G, Feeney J, J Biomol NMR. 2002 Sep;24(1):67-70. PMID:[http:// | + | NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH., Polshakov VI, Smirnov EG, Birdsall B, Kelly G, Feeney J, J Biomol NMR. 2002 Sep;24(1):67-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12449420 12449420] |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Lactobacillus casei]] | [[Category: Lactobacillus casei]] | ||
| Line 21: | Line 30: | ||
[[Category: inhibitor/enzyme complex]] | [[Category: inhibitor/enzyme complex]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:35:17 2008'' |
Revision as of 10:35, 20 March 2008
| |||||||
| Ligands: | and | ||||||
| Activity: | Dihydrofolate reductase, with EC number 1.5.1.3 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES
About this Structure
1LUD is a Single protein structure of sequence from Lactobacillus casei. Full crystallographic information is available from OCA.
Reference
NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH., Polshakov VI, Smirnov EG, Birdsall B, Kelly G, Feeney J, J Biomol NMR. 2002 Sep;24(1):67-70. PMID:12449420
Page seeded by OCA on Thu Mar 20 12:35:17 2008
