3kyr

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[[Image:3kyr.png|left|200px]]
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==Bace-1 in complex with a norstatine type inhibitor==
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<StructureSection load='3kyr' size='340' side='right' caption='[[3kyr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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{{STRUCTURE_3kyr| PDB=3kyr | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3kyr]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KYR FirstGlance]. <br>
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===Bace-1 in complex with a norstatine type inhibitor===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=038:3-[[(2S)-2-[[[(2S)-2-[[(2S)-2-[[(2S)-2-AZANYL-3-(1H-1,2,3,4-TETRAZOL-5-YLCARBONYLAMINO)PROPANOYL]AMINO]-3-METHYL-BUTANOYL]AMINO]-4-METHYL-PENTANOYL]AMINO]METHYL]-2-HYDROXY-4-PHENYL-BUTANOYL]AMINO]BENZOIC+ACID'>038</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dm6|3dm6]], [[3ixk|3ixk]], [[3ixj|3ixj]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1, BACE, KIAA1149 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr>
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[[3kyr]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYR OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kyr RCSB], [http://www.ebi.ac.uk/pdbsum/3kyr PDBsum]</span></td></tr>
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</table>
==See Also==
==See Also==
*[[Beta secretase|Beta secretase]]
*[[Beta secretase|Beta secretase]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Borkakoti, N.]]
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[[Category: Borkakoti, N]]
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[[Category: Derbyshire, D.]]
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[[Category: Derbyshire, D]]
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[[Category: Lindberg, J D.]]
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[[Category: Lindberg, J D]]
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[[Category: Nystrom, S.]]
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[[Category: Nystrom, S]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Bace]]
[[Category: Bace]]

Revision as of 08:37, 9 December 2014

Bace-1 in complex with a norstatine type inhibitor

3kyr, resolution 2.60Å

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