This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3n4i
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:3n4i.png|left|200px]] | ||
| - | |||
{{STRUCTURE_3n4i| PDB=3n4i | SCENE= }} | {{STRUCTURE_3n4i| PDB=3n4i | SCENE= }} | ||
| - | |||
===Crystal structure of the SHV-1 D104E beta-lactamase/beta-lactamase inhibitor protein (BLIP) complex=== | ===Crystal structure of the SHV-1 D104E beta-lactamase/beta-lactamase inhibitor protein (BLIP) complex=== | ||
| - | |||
{{ABSTRACT_PUBMED_21294157}} | {{ABSTRACT_PUBMED_21294157}} | ||
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/BLIP_STRCL BLIP_STRCL]] Inhibits a wide variety of beta lactamases. | ||
==About this Structure== | ==About this Structure== | ||
[[3n4i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae] and [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4I OCA]. | [[3n4i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae] and [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4I OCA]. | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Beta-lactamase|Beta-lactamase]] | ||
| - | *[[TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)|TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021294157</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021294157</ref><references group="xtra"/><references/> |
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
[[Category: Klebsiella pneumoniae]] | [[Category: Klebsiella pneumoniae]] | ||
| Line 27: | Line 22: | ||
[[Category: Reynolds, K A.]] | [[Category: Reynolds, K A.]] | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
| - | [[Category: Beta-lactamase inhibitor protein]] | ||
[[Category: Blip]] | [[Category: Blip]] | ||
| - | [[Category: Hydrolase]] | ||
[[Category: Hydrolase - hydrolase inhibitor complex]] | [[Category: Hydrolase - hydrolase inhibitor complex]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Protein-protein complex]] | [[Category: Protein-protein complex]] | ||
[[Category: Shv-1]] | [[Category: Shv-1]] | ||
Revision as of 07:35, 20 June 2013
Contents |
Crystal structure of the SHV-1 D104E beta-lactamase/beta-lactamase inhibitor protein (BLIP) complex
Template:ABSTRACT PUBMED 21294157
Function
[BLIP_STRCL] Inhibits a wide variety of beta lactamases.
About this Structure
3n4i is a 2 chain structure with sequence from Klebsiella pneumoniae and Streptomyces clavuligerus. Full crystallographic information is available from OCA.
Reference
- Hanes MS, Reynolds KA, McNamara C, Ghosh P, Bonomo RA, Kirsch JF, Handel TM. Specificity and cooperativity at beta-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions. Proteins. 2010 Dec 13. doi: 10.1002/prot.22961. PMID:21294157 doi:10.1002/prot.22961
Categories: Beta-lactamase | Klebsiella pneumoniae | Streptomyces clavuligerus | Bonomo, R A. | Ghosh, P. | Handel, T M. | Hanes, M S. | Kirsch, J F. | McNamara, C. | Reynolds, K A. | Blip | Hydrolase - hydrolase inhibitor complex | Hydrolase-hydrolase inhibitor complex | Protein-protein complex | Shv-1
