3gr6
From Proteopedia
(Difference between revisions)
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| - | [[Image:3gr6.png|left|200px]] | ||
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{{STRUCTURE_3gr6| PDB=3gr6 | SCENE= }} | {{STRUCTURE_3gr6| PDB=3gr6 | SCENE= }} | ||
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===Crystal structure of the staphylococcus aureus enoyl-acyl carrier protein reductase (fabI) in complex with NADP and triclosan=== | ===Crystal structure of the staphylococcus aureus enoyl-acyl carrier protein reductase (fabI) in complex with NADP and triclosan=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/FABI_STAAR FABI_STAAR]] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3gr6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3gr6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GR6 OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:019768684</ref><references group="xtra"/> | + | <ref group="xtra">PMID:019768684</ref><references group="xtra"/><references/> |
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[[Category: Hwang, K Y.]] | [[Category: Hwang, K Y.]] | ||
[[Category: Priyadarshi, A.]] | [[Category: Priyadarshi, A.]] | ||
Revision as of 04:05, 13 February 2014
Contents |
Crystal structure of the staphylococcus aureus enoyl-acyl carrier protein reductase (fabI) in complex with NADP and triclosan
Function
[FABI_STAAR] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
About this Structure
3gr6 is a 4 chain structure with sequence from "micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885. Full crystallographic information is available from OCA.
See Also
Reference
- Priyadarshi A, Kim EE, Hwang KY. Structural insights into Staphylococcus aureus enoyl-ACP reductase (FabI), in complex with NADP and triclosan. Proteins. 2010 Feb 1;78(2):480-6. PMID:19768684 doi:10.1002/prot.22581
