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2wj8
From Proteopedia
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| - | [[Image:2wj8.png|left|200px]] | ||
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{{STRUCTURE_2wj8| PDB=2wj8 | SCENE= }} | {{STRUCTURE_2wj8| PDB=2wj8 | SCENE= }} | ||
| + | ===Respiratory Syncitial Virus RiboNucleoProtein=== | ||
| + | {{ABSTRACT_PUBMED_19965480}} | ||
| - | === | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/NCAP_HRSVA NCAP_HRSVA]] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.<ref>PMID:9299631</ref> | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019965480</ref><ref group="xtra">PMID:017567697</ref><references group="xtra"/><references/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Human respiratory syncytial virus a strain long]] | [[Category: Human respiratory syncytial virus a strain long]] | ||
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[[Category: Duquerroy, S.]] | [[Category: Duquerroy, S.]] | ||
[[Category: Eleouet, J.]] | [[Category: Eleouet, J.]] | ||
| - | [[Category: | + | [[Category: MacLellan, K.]] |
[[Category: Rey, F A.]] | [[Category: Rey, F A.]] | ||
[[Category: Tawar, R G.]] | [[Category: Tawar, R G.]] | ||
Revision as of 19:24, 17 April 2013
Contents |
Respiratory Syncitial Virus RiboNucleoProtein
Template:ABSTRACT PUBMED 19965480
Function
[NCAP_HRSVA] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.[1]
About this Structure
2wj8 is a 40 chain structure with sequence from Escherichia coli and Human respiratory syncytial virus a strain long. Full crystallographic information is available from OCA.
See Also
Reference
- Tawar RG, Duquerroy S, Vonrhein C, Varela PF, Damier-Piolle L, Castagne N, MacLellan K, Bedouelle H, Bricogne G, Bhella D, Eleouet JF, Rey FA. Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus. Science. 2009 Nov 27;326(5957):1279-83. PMID:19965480 doi:326/5957/1279
- Maclellan K, Loney C, Yeo RP, Bhella D. The 24-angstrom structure of respiratory syncytial virus nucleocapsid protein-RNA decameric rings. J Virol. 2007 Sep;81(17):9519-24. Epub 2007 Jun 13. PMID:17567697 doi:10.1128/JVI.00526-07
- ↑ Fearns R, Peeples ME, Collins PL. Increased expression of the N protein of respiratory syncytial virus stimulates minigenome replication but does not alter the balance between the synthesis of mRNA and antigenome. Virology. 1997 Sep 15;236(1):188-201. PMID:9299631 doi:10.1006/viro.1997.8734
Categories: Escherichia coli | Human respiratory syncytial virus a strain long | Bedouelle, H. | Bhella, D. | Bricogne, G. | Castagne, N. | Damier-Piolle, L. | Duquerroy, S. | Eleouet, J. | MacLellan, K. | Rey, F A. | Tawar, R G. | Varela, P F. | Vonrhein, C. | Complex | Ribonucleoprotein | Rna | Rna binding protein | Rna binding protein rna complex | Rna binding protein-rna complex | Template-like assembly | Viral nucleoprotein | Virion
