1m6r
From Proteopedia
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| - | [[Image:1m6r.gif|left|200px]] | + | [[Image:1m6r.gif|left|200px]] |
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| - | '''Crystal structure of rGd(CGCGCG) forming hexamer Z-DNA duplex with 5'-(rG) overhang''' | + | {{Structure |
| + | |PDB= 1m6r |SIZE=350|CAPTION= <scene name='initialview01'>1m6r</scene>, resolution 1.54Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''Crystal structure of rGd(CGCGCG) forming hexamer Z-DNA duplex with 5'-(rG) overhang''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1M6R is a [ | + | 1M6R is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M6R OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of rGd(CGCGCG): a Z-DNA hexamer duplex with a 5'-(rG) overhang., Pan B, Sundaralingam M, Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):433-7. Epub 2003, Feb 21. PMID:[http:// | + | Crystal structure of rGd(CGCGCG): a Z-DNA hexamer duplex with a 5'-(rG) overhang., Pan B, Sundaralingam M, Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):433-7. Epub 2003, Feb 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12595699 12595699] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Pan, B.]] | [[Category: Pan, B.]] | ||
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[[Category: z-dna]] | [[Category: z-dna]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:39:37 2008'' |
Revision as of 10:39, 20 March 2008
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| , resolution 1.54Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of rGd(CGCGCG) forming hexamer Z-DNA duplex with 5'-(rG) overhang
Overview
The crystal structure of the heptamer rGd(CGCGCG) has been determined at 1.54 A resolution with R(work) and R(free) of 0.191 and 0.235, respectively. The crystal belongs to space group P2(1)2(1)2(1), with unit-cell parameters a = 17.96, b = 31.47, c = 44.73 A and two independent strands in the asymmetric unit. The chimera forms a Z-DNA hexamer duplex d(CGCGCG)(2), with the 5'-overhang rG invisible in the density. The replacement of rG in the 5' terminus of d(GCGCGCG) changes the reverse Hoogsteen G.G base pairing of the 5'-overhang dG (Pan et al., 1997). However, the replacement does not change the helix from Z-form to A-form or the water-structure motifs in the Z-DNA double-helical structure.
About this Structure
1M6R is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structure of rGd(CGCGCG): a Z-DNA hexamer duplex with a 5'-(rG) overhang., Pan B, Sundaralingam M, Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):433-7. Epub 2003, Feb 21. PMID:12595699
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