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1ucb
From Proteopedia
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| - | [[Image:1ucb.png|left|200px]] | ||
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{{STRUCTURE_1ucb| PDB=1ucb | SCENE= }} | {{STRUCTURE_1ucb| PDB=1ucb | SCENE= }} | ||
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===STRUCTURE OF UNCOMPLEXED FAB COMPARED TO COMPLEX (1CLY, 1CLZ)=== | ===STRUCTURE OF UNCOMPLEXED FAB COMPARED TO COMPLEX (1CLY, 1CLZ)=== | ||
| + | {{ABSTRACT_PUBMED_8683596}} | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN]] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[http://omim.org/entry/614102 614102]]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref> | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:008683596</ref><references group="xtra"/> | + | <ref group="xtra">PMID:008683596</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bajorath, J.]] | [[Category: Bajorath, J.]] | ||
Revision as of 22:54, 24 March 2013
Contents |
STRUCTURE OF UNCOMPLEXED FAB COMPARED TO COMPLEX (1CLY, 1CLZ)
Template:ABSTRACT PUBMED 8683596
Disease
[IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.[1]
About this Structure
1ucb is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sheriff S, Chang CY, Jeffrey PD, Bajorath J. X-ray structure of the uncomplexed anti-tumor antibody BR96 and comparison with its antigen-bound form. J Mol Biol. 1996 Jun 28;259(5):938-46. PMID:8683596 doi:http://dx.doi.org/10.1006/jmbi.1996.0371
- ↑ Stavnezer-Nordgren J, Kekish O, Zegers BJ. Molecular defects in a human immunoglobulin kappa chain deficiency. Science. 1985 Oct 25;230(4724):458-61. PMID:3931219
Categories: Homo sapiens | Bajorath, J. | Sheriff, S. | Anti-tumor | Antibody | Chimera | Fab | Immunoglobulin
