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1ik0
From Proteopedia
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| - | [[Image:1ik0.png|left|200px]] | ||
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{{STRUCTURE_1ik0| PDB=1ik0 | SCENE= }} | {{STRUCTURE_1ik0| PDB=1ik0 | SCENE= }} | ||
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===Solution Structure of Human IL-13=== | ===Solution Structure of Human IL-13=== | ||
| + | {{ABSTRACT_PUBMED_11419948}} | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[http://omim.org/entry/607154 607154]]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:011419948</ref><references group="xtra"/> | + | <ref group="xtra">PMID:011419948</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Diblasio, E.]] | [[Category: Diblasio, E.]] | ||
Revision as of 23:41, 24 March 2013
Contents |
Solution Structure of Human IL-13
Template:ABSTRACT PUBMED 11419948
Disease
[IL13_HUMAN] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
Function
[IL13_HUMAN] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
About this Structure
1ik0 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
See Also
Reference
- Moy FJ, Diblasio E, Wilhelm J, Powers R. Solution structure of human IL-13 and implication for receptor binding. J Mol Biol. 2001 Jun 29;310(1):219-30. PMID:11419948 doi:10.1006/jmbi.2001.4764
