1jsu

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	{{STRUCTURE_1jsu| PDB=1jsu | SCENE= }}		{{STRUCTURE_1jsu| PDB=1jsu | SCENE= }}
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	===P27(KIP1)/CYCLIN A/CDK2 COMPLEX===		===P27(KIP1)/CYCLIN A/CDK2 COMPLEX===
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	{{ABSTRACT_PUBMED_8684460}}		{{ABSTRACT_PUBMED_8684460}}

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Revision as of 10:28, 11 March 2013

Template:STRUCTURE 1jsu

Contents 1 P27(KIP1)/CYCLIN A/CDK2 COMPLEX 2 About this Structure 3 See Also 4 Reference

P27(KIP1)/CYCLIN A/CDK2 COMPLEX

Template:ABSTRACT PUBMED 8684460

About this Structure

1jsu is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Cell Division Protein Kinase 2
• Cyclin
• Intrinsically Disordered Protein

Reference

• Russo AA, Jeffrey PD, Patten AK, Massague J, Pavletich NP. Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature. 1996 Jul 25;382(6589):325-31. PMID:8684460 doi:10.1038/382325a0
• Lacy ER, Filippov I, Lewis WS, Otieno S, Xiao L, Weiss S, Hengst L, Kriwacki RW. p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding. Nat Struct Mol Biol. 2004 Apr;11(4):358-64. Epub 2004 Mar 14. PMID:15024385 doi:10.1038/nsmb746