2ix7

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[[Image:2ix7.png|left|200px]]
 
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{{STRUCTURE_2ix7| PDB=2ix7 | SCENE= }}
{{STRUCTURE_2ix7| PDB=2ix7 | SCENE= }}
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===Structure of apo-calmodulin bound to unconventional myosin V===
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{{ABSTRACT_PUBMED_17151196}}
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===STRUCTURE OF APO-CALMODULIN BOUND TO UNCONVENTIONAL MYOSIN V===
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==Function==
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[[http://www.uniprot.org/uniprot/MYO5A_MOUSE MYO5A_MOUSE]] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:22908308</ref>
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{{ABSTRACT_PUBMED_17151196}}
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==About this Structure==
==About this Structure==
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[[2ix7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX7 OCA].
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[[2ix7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX7 OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:017151196</ref><references group="xtra"/>
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<ref group="xtra">PMID:017151196</ref><references group="xtra"/><references/>
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[[Category: Mus musculus]]
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[[Category: Lk3 transgenic mice]]
[[Category: Cohen, C.]]
[[Category: Cohen, C.]]
[[Category: Gaucher, J F.]]
[[Category: Gaucher, J F.]]

Revision as of 06:01, 4 December 2013

Template:STRUCTURE 2ix7

Contents

Structure of apo-calmodulin bound to unconventional myosin V

Template:ABSTRACT PUBMED 17151196

Function

[MYO5A_MOUSE] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.[1]

About this Structure

2ix7 is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

See Also

Reference

  • Houdusse A, Gaucher JF, Krementsova E, Mui S, Trybus KM, Cohen C. Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19326-31. Epub 2006 Dec 6. PMID:17151196
  1. ↑ Chen Y, Wang Y, Zhang J, Deng Y, Jiang L, Song E, Wu XS, Hammer JA, Xu T, Lippincott-Schwartz J. Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol. 2012 Aug 20;198(4):545-60. doi: 10.1083/jcb.201111091. PMID:22908308 doi:10.1083/jcb.201111091

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