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3rqo
From Proteopedia
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| - | [[Image:3rqo.png|left|200px]] | ||
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{{STRUCTURE_3rqo| PDB=3rqo | SCENE= }} | {{STRUCTURE_3rqo| PDB=3rqo | SCENE= }} | ||
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===Structure of the endothelial nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((1S,2R/1R,2S)-2-(3-Clorophenyl)cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine=== | ===Structure of the endothelial nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((1S,2R/1R,2S)-2-(3-Clorophenyl)cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine=== | ||
| + | {{ABSTRACT_PUBMED_23352768}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/NOS3_BOVIN NOS3_BOVIN]] Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. | ||
==About this Structure== | ==About this Structure== | ||
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*[[Nitric Oxide Synthase|Nitric Oxide Synthase]] | *[[Nitric Oxide Synthase|Nitric Oxide Synthase]] | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
| - | [[Category: Nitric-oxide synthase]] | ||
[[Category: Delker, S L.]] | [[Category: Delker, S L.]] | ||
[[Category: Li, H.]] | [[Category: Li, H.]] | ||
Revision as of 09:39, 24 April 2013
Contents |
Structure of the endothelial nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((1S,2R/1R,2S)-2-(3-Clorophenyl)cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Template:ABSTRACT PUBMED 23352768
Function
[NOS3_BOVIN] Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
About this Structure
3rqo is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
