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2acl

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Revision as of 14:46, 20 October 2012

Image:2acl.png

Template:STRUCTURE 2acl

Contents

Liver X-Receptor alpha Ligand Binding Domain with SB313987

Template:ABSTRACT PUBMED 16107141

About this Structure

2acl is a 8 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  • Jaye MC, Krawiec JA, Campobasso N, Smallwood A, Qiu C, Lu Q, Kerrigan JJ, De Los Frailes Alvaro M, Laffitte B, Liu WS, Marino JP Jr, Meyer CR, Nichols JA, Parks DJ, Perez P, Sarov-Blat L, Seepersaud SD, Steplewski KM, Thompson SK, Wang P, Watson MA, Webb CL, Haigh D, Caravella JA, Macphee CH, Willson TM, Collins JL. Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure. J Med Chem. 2005 Aug 25;48(17):5419-22. PMID:16107141 doi:10.1021/jm050532w

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OCA

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