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3d4y

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[[Image:3d4y.png|left|200px]]
 
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{{STRUCTURE_3d4y| PDB=3d4y | SCENE= }}
{{STRUCTURE_3d4y| PDB=3d4y | SCENE= }}
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===GOLGI MANNOSIDASE II complex with mannoimidazole===
===GOLGI MANNOSIDASE II complex with mannoimidazole===
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{{ABSTRACT_PUBMED_18759458}}
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{{ABSTRACT_PUBMED_18759458}}
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==Function==
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[[http://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:018759458</ref><ref group="xtra">PMID:019101978</ref><references group="xtra"/>
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<ref group="xtra">PMID:018759458</ref><references group="xtra"/><references/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]

Revision as of 05:42, 6 November 2013

Template:STRUCTURE 3d4y

Contents

GOLGI MANNOSIDASE II complex with mannoimidazole

Template:ABSTRACT PUBMED 18759458

Function

[MAN2_DROME] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).

About this Structure

3d4y is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

See Also

Reference

  • Kuntz DA, Tarling CA, Withers SG, Rose DR. Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen. Biochemistry. 2008 Sep 23;47(38):10058-68. Epub 2008 Aug 30. PMID:18759458 doi:10.1021/bi8010785

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OCA

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