3d4y
From Proteopedia
(Difference between revisions)
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- | [[Image:3d4y.png|left|200px]] | ||
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{{STRUCTURE_3d4y| PDB=3d4y | SCENE= }} | {{STRUCTURE_3d4y| PDB=3d4y | SCENE= }} | ||
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===GOLGI MANNOSIDASE II complex with mannoimidazole=== | ===GOLGI MANNOSIDASE II complex with mannoimidazole=== | ||
+ | {{ABSTRACT_PUBMED_18759458}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:018759458</ref>< | + | <ref group="xtra">PMID:018759458</ref><references group="xtra"/><references/> |
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]] | [[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]] |
Revision as of 05:42, 6 November 2013
Contents |
GOLGI MANNOSIDASE II complex with mannoimidazole
Template:ABSTRACT PUBMED 18759458
Function
[MAN2_DROME] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
About this Structure
3d4y is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
See Also
Reference
- Kuntz DA, Tarling CA, Withers SG, Rose DR. Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen. Biochemistry. 2008 Sep 23;47(38):10058-68. Epub 2008 Aug 30. PMID:18759458 doi:10.1021/bi8010785