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3kxu

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[[Image:3kxu.png|left|200px]]
 
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{{STRUCTURE_3kxu| PDB=3kxu | SCENE= }}
{{STRUCTURE_3kxu| PDB=3kxu | SCENE= }}
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===Crystal structure of human ferritin FTL498InsTC pathogenic mutant===
===Crystal structure of human ferritin FTL498InsTC pathogenic mutant===
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{{ABSTRACT_PUBMED_20159981}}
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{{ABSTRACT_PUBMED_20159981}}
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==Function==
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[[http://www.uniprot.org/uniprot/Q6S4P3_HUMAN Q6S4P3_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis (By similarity).[RuleBase:RU000622]
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:020159981</ref><references group="xtra"/>
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<ref group="xtra">PMID:020159981</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arosio, P.]]
[[Category: Arosio, P.]]

Revision as of 20:11, 24 March 2013

Template:STRUCTURE 3kxu

Contents

Crystal structure of human ferritin FTL498InsTC pathogenic mutant

Template:ABSTRACT PUBMED 20159981

Function

[Q6S4P3_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis (By similarity).[RuleBase:RU000622]

About this Structure

3kxu is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Luscieti S, Santambrogio P, Langlois d'Estaintot B, Granier T, Cozzi A, Poli M, Gallois B, Finazzi D, Cattaneo A, Levi S, Arosio P. Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. J Biol Chem. 2010 Apr 16;285(16):11948-57. Epub 2010 Feb 16. PMID:20159981 doi:10.1074/jbc.M109.096404

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OCA

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