3heg

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	{{STRUCTURE_3heg| PDB=3heg | SCENE= }}		{{STRUCTURE_3heg| PDB=3heg | SCENE= }}
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	===P38 in complex with Sorafenib===		===P38 in complex with Sorafenib===
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	{{ABSTRACT_PUBMED_20337484}}		{{ABSTRACT_PUBMED_20337484}}

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Revision as of 10:14, 11 March 2013

Template:STRUCTURE 3heg

Contents 1 P38 in complex with Sorafenib 2 About this Structure 3 See Also 4 Reference

P38 in complex with Sorafenib

Template:ABSTRACT PUBMED 20337484

About this Structure

3heg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Mitogen-activated protein kinase
• Sorafenib

Reference

• Namboodiri HV, Bukhtiyarova M, Ramcharan J, Karpusas M, Lee Y, Springman EB. Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry. 2010 May 4;49(17):3611-8. PMID:20337484 doi:10.1021/bi100070r