1n6g
From Proteopedia
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| - | [[Image:1n6g.gif|left|200px]] | + | [[Image:1n6g.gif|left|200px]] |
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| - | '''The structure of immature Dengue-2 prM particles''' | + | {{Structure |
| + | |PDB= 1n6g |SIZE=350|CAPTION= <scene name='initialview01'>1n6g</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''The structure of immature Dengue-2 prM particles''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1N6G is a [ | + | 1N6G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dengue_virus_type_3 Dengue virus type 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N6G OCA]. |
==Reference== | ==Reference== | ||
| - | Structures of immature flavivirus particles., Zhang Y, Corver J, Chipman PR, Zhang W, Pletnev SV, Sedlak D, Baker TS, Strauss JH, Kuhn RJ, Rossmann MG, EMBO J. 2003 Jun 2;22(11):2604-13. PMID:[http:// | + | Structures of immature flavivirus particles., Zhang Y, Corver J, Chipman PR, Zhang W, Pletnev SV, Sedlak D, Baker TS, Strauss JH, Kuhn RJ, Rossmann MG, EMBO J. 2003 Jun 2;22(11):2604-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12773377 12773377] |
[[Category: Dengue virus type 3]] | [[Category: Dengue virus type 3]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: prm particle]] | [[Category: prm particle]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:52:49 2008'' |
Revision as of 10:52, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
The structure of immature Dengue-2 prM particles
Overview
Structures of prM-containing dengue and yellow fever virus particles were determined to 16 and 25 A resolution, respectively, by cryoelectron microscopy and image reconstruction techniques. The closely similar structures show 60 icosahedrally organized trimeric spikes on the particle surface. Each spike consists of three prM:E heterodimers, where E is an envelope glycoprotein and prM is the precursor to the membrane protein M. The pre-peptide components of the prM proteins in each spike cover the fusion peptides at the distal ends of the E glycoproteins in a manner similar to the organization of the glycoproteins in the alphavirus spikes. Each heterodimer is associated with an E and a prM transmembrane density. These transmembrane densities represent either an EE or prMprM antiparallel coiled coil by which each protein spans the membrane twice, leaving the C-terminus of each protein on the exterior of the viral membrane, consistent with the predicted membrane-spanning domains of the unprocessed polyprotein.
About this Structure
1N6G is a Single protein structure of sequence from Dengue virus type 3. Full crystallographic information is available from OCA.
Reference
Structures of immature flavivirus particles., Zhang Y, Corver J, Chipman PR, Zhang W, Pletnev SV, Sedlak D, Baker TS, Strauss JH, Kuhn RJ, Rossmann MG, EMBO J. 2003 Jun 2;22(11):2604-13. PMID:12773377
Page seeded by OCA on Thu Mar 20 12:52:49 2008
