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2eiz

From Proteopedia

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[[Image:2eiz.png|left|200px]]
 
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{{STRUCTURE_2eiz| PDB=2eiz | SCENE= }}
{{STRUCTURE_2eiz| PDB=2eiz | SCENE= }}
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===Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex===
===Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex===
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{{ABSTRACT_PUBMED_18227432}}
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{{ABSTRACT_PUBMED_18227432}}
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==Function==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
==About this Structure==
==About this Structure==
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[[2eiz]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIZ OCA].
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[[2eiz]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIZ OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:018227432</ref><references group="xtra"/>
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<ref group="xtra">PMID:018227432</ref><references group="xtra"/><references/>
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[[Category: Gallus gallus]]
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[[Category: Chick]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
[[Category: Kondo, H.]]
[[Category: Kondo, H.]]

Revision as of 14:13, 3 March 2014

Template:STRUCTURE 2eiz

Contents

Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex

Template:ABSTRACT PUBMED 18227432

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

About this Structure

2eiz is a 3 chain structure with sequence from Chick and Human. Full crystallographic information is available from OCA.

See Also

Reference

  • Nakanishi T, Tsumoto K, Yokota A, Kondo H, Kumagai I. Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10. Protein Sci. 2008 Feb;17(2):261-70. PMID:18227432 doi:http://dx.doi.org/17/2/261
  1. ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

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