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3t72

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[[Image:3t72.png|left|200px]]
 
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{{STRUCTURE_3t72| PDB=3t72 | SCENE= }}
{{STRUCTURE_3t72| PDB=3t72 | SCENE= }}
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===PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex===
===PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex===
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{{ABSTRACT_PUBMED_21829166}}
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{{ABSTRACT_PUBMED_21829166}}
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==Function==
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[[http://www.uniprot.org/uniprot/RPOD_ECOLI RPOD_ECOLI]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium. [[http://www.uniprot.org/uniprot/PHOB_ECOLI PHOB_ECOLI]] This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.
==About this Structure==
==About this Structure==
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[[3t72]] is a 50 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T72 OCA].
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[[3t72]] is a 50 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T72 OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:021829166</ref><references group="xtra"/>
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<ref group="xtra">PMID:021829166</ref><references group="xtra"/><references/>
[[Category: DNA-directed RNA polymerase]]
[[Category: DNA-directed RNA polymerase]]
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[[Category: Escherichia coli]]
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[[Category: Ecoli]]
[[Category: Bernues, J.]]
[[Category: Bernues, J.]]
[[Category: Blanco, A G.]]
[[Category: Blanco, A G.]]
[[Category: Canals, A.]]
[[Category: Canals, A.]]
[[Category: Coll, M.]]
[[Category: Coll, M.]]
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[[Category: Sola , M.]]
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[[Category: Sola, M.]]
[[Category: Dna-binding]]
[[Category: Dna-binding]]
[[Category: Transcription activation]]
[[Category: Transcription activation]]
[[Category: Transcription-dna complex]]
[[Category: Transcription-dna complex]]
[[Category: Winged-helix motif]]
[[Category: Winged-helix motif]]

Revision as of 07:48, 18 December 2013

Template:STRUCTURE 3t72

Contents

PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex

Template:ABSTRACT PUBMED 21829166

Function

[RPOD_ECOLI] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium. [PHOB_ECOLI] This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

About this Structure

3t72 is a 50 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

See Also

Reference

  • Blanco AG, Canals A, Bernues J, Sola M, Coll M. The structure of a transcription activation subcomplex reveals how sigma(70) is recruited to PhoB promoters. EMBO J. 2011 Aug 9;30(18):3776-85. doi: 10.1038/emboj.2011.271. PMID:21829166 doi:10.1038/emboj.2011.271

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