This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3lds
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:3lds.png|left|200px]] | ||
| - | |||
{{STRUCTURE_3lds| PDB=3lds | SCENE= }} | {{STRUCTURE_3lds| PDB=3lds | SCENE= }} | ||
| - | |||
===Crystal structure of RB69 gp43 with DNA and dATP opposite 8-oxoG=== | ===Crystal structure of RB69 gp43 with DNA and dATP opposite 8-oxoG=== | ||
| + | {{ABSTRACT_PUBMED_20166748}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. | ||
==About this Structure== | ==About this Structure== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:020166748</ref><references group="xtra"/> | + | <ref group="xtra">PMID:020166748</ref><references group="xtra"/><references/> |
[[Category: DNA-directed DNA polymerase]] | [[Category: DNA-directed DNA polymerase]] | ||
[[Category: Enterobacteria phage rb69]] | [[Category: Enterobacteria phage rb69]] | ||
Revision as of 06:34, 16 May 2013
Contents |
Crystal structure of RB69 gp43 with DNA and dATP opposite 8-oxoG
Template:ABSTRACT PUBMED 20166748
Function
[DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
About this Structure
3lds is a 3 chain structure with sequence from Enterobacteria phage rb69. Full crystallographic information is available from OCA.
See Also
Reference
- Hogg M, Rudnicki J, Midkiff J, Reha-Krantz L, Doublie S, Wallace SS. Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Biochemistry. 2010 Mar 23;49(11):2317-25. PMID:20166748 doi:10.1021/bi901488d
