1nw3

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[[Image:1nw3.png|left|200px]]
 
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{{STRUCTURE_1nw3| PDB=1nw3 | SCENE= }}
{{STRUCTURE_1nw3| PDB=1nw3 | SCENE= }}
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===Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase===
===Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase===
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{{ABSTRACT_PUBMED_12628190}}
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{{ABSTRACT_PUBMED_12628190}}
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==Function==
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[[http://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN]] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
==About this Structure==
==About this Structure==
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[[1nw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NW3 OCA].
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[[1nw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NW3 OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:012628190</ref><references group="xtra"/>
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<ref group="xtra">PMID:012628190</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Feng, Q.]]
[[Category: Feng, Q.]]
[[Category: Li, Z H.]]
[[Category: Li, Z H.]]

Revision as of 07:26, 16 April 2014

Template:STRUCTURE 1nw3

Contents

Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

Template:ABSTRACT PUBMED 12628190

Function

[DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

About this Structure

1nw3 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See Also

Reference

  • Min J, Feng Q, Li Z, Zhang Y, Xu RM. Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase. Cell. 2003 Mar 7;112(5):711-23. PMID:12628190

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