2jgk
From Proteopedia
(Difference between revisions)
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| - | [[Image:2jgk.png|left|200px]] | ||
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{{STRUCTURE_2jgk| PDB=2jgk | SCENE= }} | {{STRUCTURE_2jgk| PDB=2jgk | SCENE= }} | ||
| + | ===Crystal structure of mouse acetylcholinesterase inhibited by aged fenamiphos=== | ||
| + | {{ABSTRACT_PUBMED_17402711}} | ||
| - | === | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. | |
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2jgk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[2jgk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGK OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:017402711</ref><references group="xtra"/> | + | <ref group="xtra">PMID:017402711</ref><references group="xtra"/><references/> |
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Ekstrom, F.]] | [[Category: Ekstrom, F.]] | ||
[[Category: Hornberg, A.]] | [[Category: Hornberg, A.]] | ||
[[Category: Tunemalm, A K.]] | [[Category: Tunemalm, A K.]] | ||
| - | [[Category: Acetylcholinesterase]] | ||
[[Category: Aging]] | [[Category: Aging]] | ||
| - | [[Category: Fenamipho]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 06:16, 29 January 2014
Contents |
Crystal structure of mouse acetylcholinesterase inhibited by aged fenamiphos
Template:ABSTRACT PUBMED 17402711
Function
[ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
About this Structure
2jgk is a 2 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.
See Also
Reference
- Hornberg A, Tunemalm AK, Ekstrom F. Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state. Biochemistry. 2007 Apr 24;46(16):4815-25. Epub 2007 Apr 3. PMID:17402711 doi:http://dx.doi.org/10.1021/bi0621361
