3qi3
From Proteopedia
(Difference between revisions)
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| - | [[Image:3qi3.png|left|200px]] | ||
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{{STRUCTURE_3qi3| PDB=3qi3 | SCENE= }} | {{STRUCTURE_3qi3| PDB=3qi3 | SCENE= }} | ||
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===Crystal structure of PDE9A(Q453E) in complex with inhibitor BAY73-6691=== | ===Crystal structure of PDE9A(Q453E) in complex with inhibitor BAY73-6691=== | ||
| + | {{ABSTRACT_PUBMED_21483814}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/PDE9A_HUMAN PDE9A_HUMAN]] Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.<ref>PMID:18757755</ref> | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3qi3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3qi3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QI3 OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021483814</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021483814</ref><references group="xtra"/><references/> |
[[Category: 3',5'-cyclic-GMP phosphodiesterase]] | [[Category: 3',5'-cyclic-GMP phosphodiesterase]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Hou, J.]] | [[Category: Hou, J.]] | ||
[[Category: Ke, H.]] | [[Category: Ke, H.]] | ||
Revision as of 06:18, 13 November 2013
Contents |
Crystal structure of PDE9A(Q453E) in complex with inhibitor BAY73-6691
Template:ABSTRACT PUBMED 21483814
Function
[PDE9A_HUMAN] Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.[1]
About this Structure
3qi3 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Reference
- Hou J, Xu J, Liu M, Zhao R, Luo HB, Ke H. Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine. PLoS One. 2011 Mar 31;6(3):e18092. PMID:21483814 doi:10.1371/journal.pone.0018092
