3u2c
From Proteopedia
(Difference between revisions)
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| - | [[Image:3u2c.png|left|200px]] | ||
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{{STRUCTURE_3u2c| PDB=3u2c | SCENE= }} | {{STRUCTURE_3u2c| PDB=3u2c | SCENE= }} | ||
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===Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution=== | ===Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN]] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021997888</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021997888</ref><references group="xtra"/><references/> |
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 12:41, 3 July 2013
Contents |
Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution
Function
[ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
About this Structure
3u2c is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Steuber H. An Old NSAID Revisited: Crystal Structure of Aldose Reductase in Complex with Sulindac at 1.0 A Supports a Novel Mechanism for its Anticancer and Antiproliferative Effects. ChemMedChem. 2011 Oct 13. doi: 10.1002/cmdc.201100374. PMID:21997888 doi:10.1002/cmdc.201100374
