1zx1

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[[Image:1zx1.png|left|200px]]
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==Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954==
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<StructureSection load='1zx1' size='340' side='right' caption='[[1zx1]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
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{{STRUCTURE_1zx1| PDB=1zx1 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1zx1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZX1 FirstGlance]. <br>
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===Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954===
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CB1:5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE'>CB1</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qr1|1qr1]], [[1qr2|1qr2]]</td></tr>
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{{ABSTRACT_PUBMED_016192279}}
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NQO2, NMOR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zx1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zx1 RCSB], [http://www.ebi.ac.uk/pdbsum/1zx1 PDBsum]</span></td></tr>
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==About this Structure==
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<table>
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[[1zx1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZX1 OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/1zx1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Quinone reductase|Quinone reductase]]
*[[Quinone reductase|Quinone reductase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016192279</ref><ref group="xtra">PMID:020630857</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith, C.]]

Revision as of 03:34, 29 September 2014

Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954

1zx1, resolution 2.16Å

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OCA

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