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2isi

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[[Image:2isi.png|left|200px]]
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==Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand==
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<StructureSection load='2isi' size='340' side='right' caption='[[2isi]], [[Resolution|resolution]] 2.76&Aring;' scene=''>
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{{STRUCTURE_2isi| PDB=2isi | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2isi]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ISI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ISI FirstGlance]. <br>
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===Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand===
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hd7|1hd7]], [[1e9n|1e9n]], [[1dew|1dew]], [[1de9|1de9]], [[1de8|1de8]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-(apurinic_or_apyrimidinic_site)_lyase DNA-(apurinic or apyrimidinic site) lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.99.18 4.2.99.18] </span></td></tr>
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==About this Structure==
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2isi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2isi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2isi RCSB], [http://www.ebi.ac.uk/pdbsum/2isi PDBsum]</span></td></tr>
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[[2isi]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ISI OCA].
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/is/2isi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Apurinic/Apyrimidinic Endonuclease-1|Apurinic/Apyrimidinic Endonuclease-1]]
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*[[Apurinic-Apyrimidinic Endonuclease-1|Apurinic-Apyrimidinic Endonuclease-1]]
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*[[DNA polymerase|DNA polymerase]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Agarwal, R.]]
[[Category: Agarwal, R.]]

Revision as of 03:40, 29 September 2014

Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand

2isi, resolution 2.76Å

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