2c7o

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[[Image:2c7o.png|left|200px]]
 
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{{STRUCTURE_2c7o| PDB=2c7o | SCENE= }}
{{STRUCTURE_2c7o| PDB=2c7o | SCENE= }}
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===HhaI DNA methyltransferase complex with 13mer oligonucleotide containing 2-aminopurine adjacent to the target base (PCGC:GMGC) and SAH===
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{{ABSTRACT_PUBMED_16340006}}
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===HHAI DNA METHYLTRANSFERASE COMPLEX WITH 13MER OLIGONUCLEOTIDE CONTAINING 2-AMINOPURINE ADJACENT TO THE TARGET BASE (PCGC:GMGC) AND SAH===
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==Function==
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[[http://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH]] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
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{{ABSTRACT_PUBMED_16340006}}
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==About this Structure==
==About this Structure==
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[[2c7o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7O OCA].
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[[2c7o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7O OCA].
==See Also==
==See Also==
*[[DNA methyltransferase|DNA methyltransferase]]
*[[DNA methyltransferase|DNA methyltransferase]]
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*[[HhaI DNA methyltransferase|HhaI DNA methyltransferase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:016340006</ref><references group="xtra"/>
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<ref group="xtra">PMID:016340006</ref><references group="xtra"/><references/>
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[[Category: Haemophilus haemolyticus]]
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[[Category: Bacillus x pritchett and stillman 1919]]
[[Category: Daujotyte, D.]]
[[Category: Daujotyte, D.]]
[[Category: Grazulis, S.]]
[[Category: Grazulis, S.]]
[[Category: Base flipping]]
[[Category: Base flipping]]
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[[Category: Dna methyltransferase]]
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[[Category: Transferase restriction system]]
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[[Category: Methyltransferase]]
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[[Category: Transferase-dna complex]]
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[[Category: Restriction system]]
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[[Category: Transferase]]
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Revision as of 06:23, 29 January 2014

Template:STRUCTURE 2c7o

Contents

HhaI DNA methyltransferase complex with 13mer oligonucleotide containing 2-aminopurine adjacent to the target base (PCGC:GMGC) and SAH

Template:ABSTRACT PUBMED 16340006

Function

[MTH1_HAEPH] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.

About this Structure

2c7o is a 3 chain structure with sequence from "bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919. Full crystallographic information is available from OCA.

See Also

Reference

  • Neely RK, Daujotyte D, Grazulis S, Magennis SW, Dryden DT, Klimasauskas S, Jones AC. Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI-DNA complexes. Nucleic Acids Res. 2005 Dec 9;33(22):6953-60. Print 2005. PMID:16340006 doi:http://dx.doi.org/33/22/6953

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