1mqt

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[[Image:1mqt.png|left|200px]]
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==Swine Vesicular Disease Virus coat protein==
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<StructureSection load='1mqt' size='340' side='right' caption='[[1mqt]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1mqt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Swine_vesicular_disease_virus Swine vesicular disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MQT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MQT FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPL:OCTANOIC+ACID+(2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE'>SPL</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1cov|1cov]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mqt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mqt RCSB], [http://www.ebi.ac.uk/pdbsum/1mqt PDBsum]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mq/1mqt_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of swine vesicular disease virus (SVDV) was solved and refined at a 3.0-A resolution by X-ray crystallography to gain information about the role of sequence changes that occurred as this virus evolved from the parental human pathogen coxsackievirus B5 (CVB5). These amino acid substitutions can be clustered in five distinct regions: (i) the antigenic sites, (ii) the hydrophobic pocket of the VP1 beta-sandwich, (iii) the putative CAR binding site, (iv) the putative heparan sulfate binding site, and (v) the fivefold axis. The VP1 pocket is occupied by a branched pocket factor, apparently different from that present in the closely related virus CVB3 and in other picornaviruses. This finding may be relevant for the design of new antiviral compounds against this site. Density consistent with the presence of ions was observed on the fivefold and threefold axes. The structure also provided an accurate description of the putative receptor binding sites.
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{{STRUCTURE_1mqt| PDB=1mqt | SCENE= }}
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Structure of swine vesicular disease virus: mapping of changes occurring during adaptation of human coxsackie B5 virus to infect swine.,Verdaguer N, Jimenez-Clavero MA, Fita I, Ley V J Virol. 2003 Sep;77(18):9780-9. PMID:12941886<ref>PMID:12941886</ref>
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===Swine Vesicular Disease Virus coat protein===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_12941886}}
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==About this Structure==
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[[1mqt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Swine_vesicular_disease_virus Swine vesicular disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MQT OCA].
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==See Also==
==See Also==
*[[Virus coat protein|Virus coat protein]]
*[[Virus coat protein|Virus coat protein]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:012941886</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Swine vesicular disease virus]]
[[Category: Swine vesicular disease virus]]
[[Category: Fita, I.]]
[[Category: Fita, I.]]

Revision as of 16:11, 28 September 2014

Swine Vesicular Disease Virus coat protein

1mqt, resolution 3.30Å

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