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3h2v

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[[Image:3h2v.png|left|200px]]
 
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{{STRUCTURE_3h2v| PDB=3h2v | SCENE= }}
{{STRUCTURE_3h2v| PDB=3h2v | SCENE= }}
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===Human raver1 RRM1 domain in complex with human vinculin tail domain Vt===
===Human raver1 RRM1 domain in complex with human vinculin tail domain Vt===
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{{ABSTRACT_PUBMED_19523901}}
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{{ABSTRACT_PUBMED_19523901}}
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==Function==
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[[http://www.uniprot.org/uniprot/RAVR1_HUMAN RAVR1_HUMAN]] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:019523901</ref><references group="xtra"/>
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<ref group="xtra">PMID:019523901</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Izard, T.]]
[[Category: Izard, T.]]

Revision as of 23:42, 24 March 2013

Template:STRUCTURE 3h2v

Contents

Human raver1 RRM1 domain in complex with human vinculin tail domain Vt

Template:ABSTRACT PUBMED 19523901

Function

[RAVR1_HUMAN] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).

About this Structure

3h2v is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lee JH, Rangarajan ES, Yogesha SD, Izard T. Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure. 2009 Jun 10;17(6):833-42. PMID:19523901 doi:S0969-2126(09)00193-2

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OCA

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